REGENERATIVE AESTHETICS

Polynucleotide Treatments

Regenerative skin repair at a cellular level. Advanced injectable treatments that activate your skin's natural repair processes — restoring hydration, elasticity and collagen for healthier, stronger-looking skin from within.

From £190. Consultation included.

WHY POLYNUCLEOTIDE TREATMENTS

Restore skin health through regeneration, not volume

Cellular Skin Regeneration

Stimulates fibroblasts to repair and strengthen the skin at a cellular level — building healthier, more resilient tissue from the inside out rather than masking concerns from the surface.

Improves Skin Quality, Not Shape

Enhances hydration, texture, elasticity and tone without adding volume or altering your features. The architecture of your face stays entirely your own — only better.

Natural, Progressive Results

Gradual improvement for healthier, stronger-looking skin that continues to develop over weeks as collagen rebuilds. Never sudden. Never overdone. Always uniquely you.

Close-up of a woman receiving a cosmetic injection under her eye.

THE TREATMENT

What are polynucleotides?

Injectable treatments derived from purified DNA fragments that activate the skin's natural repair processes. By stimulating fibroblast activity, they improve hydration, elasticity and collagen production while strengthening the skin barrier from within. At Ascot Medi Spa we use premium brands including Nucleofil and Vitara, selected for their quality safety and proven results. Unlike dermal fillers which add volume polynucleotides work at a cellular level to improve the actual quality of your skin. The result is gradual, natural and focused on long-term skin health rather than instant change.

Suitable for the face, neck, décolletage and the delicate under-eye area.

What it helps with

A woman with closed eyes and smooth skin, adorned with small decorative pearls around her eye in a beauty or skincare portrait.

WHAT TO EXPECT

The Experience

Treatment Time

30–60 minutes

Comfort

Mild discomfort; numbing cream available

Downtime

Minimal — return to normal activities immediately

Results

Develop progressively over 4–8 weeks

A young woman with closed eyes and a gentle smile, touching her neck with her hand, against a neutral background.

PRICING

Treatment Pricing

All treatments include a thorough consultation with one of our experienced practitioners to assess your skin and tailor a plan to your goals.

Face & Neck

Treatment

Full Face & Neck

Under-Eye

Duration

1 hour

30 mins

Price

£225

£190

SAVE MORE

Course Packages

A course of 3 sessions, spaced 3–4 weeks apart, delivers optimal results. Save when booking ahead.

Full Face & Neck Course of 3

£200 per session · Full Face & Neck

£600

Our recommended starting course for noticeable, lasting skin quality improvement.

Under-Eye · Course of 3

£170 per session · Under ete

£510

Targeted regeneration for under-eye crepiness and dark circles.

COMMON QUESTIONS

FAQ

  • Most clients require 2–3 sessions, spaced 2–4 weeks apart.

  • Polynucleotides work progressively. You may notice improved hydration and smoother texture within the first 1–2 weeks. The full effect develops over 4–8 weeks as fibroblast activity increases and new collagen forms. Unlike fillers, the change is gradual, refined and uniquely natural-looking — your skin simply looks healthier rather than altered.

  • Once a course is complete, results typically last 6–9 months. Because polynucleotides genuinely improve the underlying quality of your skin rather than masking concerns, benefits compound over time when treatment is maintained — your skin keeps getting healthier with each course rather than simply returning to baseline.

  • Downtime is minimal — you can return to normal activities immediately. Small injection bumps usually settle within a few hours, and any minor redness or bruising typically resolves within 24–48 hours. We recommend avoiding makeup, exercise, alcohol and direct heat (sauna, sunbed) for 12–24 hours afterwards.

  • Skin boosters (such as Profhilo) hydrate and lift using hyaluronic acid. Dermal fillers add volume and reshape contours. Polynucleotides are different — they're regenerative. They don't add anything to your face; they signal your own cells to repair and rebuild, improving skin quality at a cellular level. Many clients combine treatments for layered results, and we can advise on the best combination during consultation.

  • “Amazing clinics, so professional and safe feeling. Felt looked after the whole way through and would definitely recommend. Not to forget very reasonable pricing for the quality of work”

    — Google Review

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  • "I had an amazing experience at this beauty salon! From the moment I arrived, the team was incredibly welcoming and helpful. Outstanding service from start to finish. I couldn’t recommend them enough!"

    — Google Review

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  • "I always have an absolutely amazing experience at Ascot Medi-Spa. The staff are beyond friendly — warm, welcoming, and truly passionate about what they do. They customise every treatment perfectly to my needs, and my results last far longer than I ever expect. I’m consistently blown away and couldn’t recommend them more!"

    — Google Review

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  • "I had an amazing experience at Ascot Medi Spa! From the moment I walked in, the atmosphere was calm, welcoming, and beautifully designed. The staff were incredibly professional, knowledgeable, and attentive-they really took the time to understand my goals and explain each step of the treatment. Will be returning for sure"

    — Google Review

    ⭐ ⭐ ⭐ ⭐ ⭐

READY?

Regenerate naturally. Restore from within.

Book your free consultation to discuss whether polynucleotide treatments are right for your skin.

Make an Enquiry

Have a question or would like to learn more about our treatments?

Send us a message - our friendly team will be delighted to assist and help you take the next step towards radiant, confident skin.