REGENERATIVE AESTHETICS

Polynucleotide Treatments

Regenerative skin repair at a cellular level. Advanced injectable treatments that activate your skin's natural repair processes — restoring hydration, elasticity and collagen for healthier, stronger-looking skin from within.

From £190. Consultation included.

WHY POLYNUCLEOTIDE TREATMENTS

Restore skin health through regeneration, not volume

Cellular Skin Regeneration

Stimulates fibroblasts to repair and strengthen the skin at a cellular level — building healthier, more resilient tissue from the inside out rather than masking concerns from the surface.

Improves Skin Quality, Not Shape

Enhances hydration, texture, elasticity and tone without adding volume or altering your features. The architecture of your face stays entirely your own — only better.

Natural, Progressive Results

Gradual improvement for healthier, stronger-looking skin that continues to develop over weeks as collagen rebuilds. Never sudden. Never overdone. Always uniquely you.

Close-up of a woman receiving a cosmetic injection under her eye.

THE TREATMENT

What are polynucleotides?

Injectable treatments derived from purified DNA fragments that activate the skin's natural repair processes. By stimulating fibroblast activity, they improve hydration, elasticity and collagen production while strengthening the skin barrier from within. At Ascot Medi Spa we use premium brands including Nucleofil and Vitara, selected for their quality safety and proven results. Unlike dermal fillers which add volume polynucleotides work at a cellular level to improve the actual quality of your skin. The result is gradual, natural and focused on long-term skin health rather than instant change.

Suitable for the face, neck, décolletage and the delicate under-eye area.

What it helps with

A woman with closed eyes and smooth skin, adorned with small decorative pearls around her eye in a beauty or skincare portrait.

WHAT TO EXPECT

The Experience

Treatment Time

30–60 minutes

Comfort

Mild discomfort; numbing cream available

Downtime

Minimal — return to normal activities immediately

Results

Develop progressively over 4–8 weeks

A young woman with closed eyes and a gentle smile, touching her neck with her hand, against a neutral background.

PRICING

Treatment Pricing

All treatments include a thorough consultation with one of our experienced practitioners to assess your skin and tailor a plan to your goals.

Face & Neck

Treatment

Full Face & Neck

Under-Eye

Duration

1 hour

30 mins

Price

£225

£190

SAVE MORE

Course Packages

A course of 3 sessions, spaced 3–4 weeks apart, delivers optimal results. Save when booking ahead.

Full Face & Neck Course of 3

£200 per session · Full Face & Neck

£600

Our recommended starting course for noticeable, lasting skin quality improvement.

Under-Eye · Course of 3

£170 per session · Under ete

£510

Targeted regeneration for under-eye crepiness and dark circles.

COMMON QUESTIONS

FAQ

  • "The best aesthetics and facials in Berkshire. I’ve had several treatments including polynucleotides, Botox, hydrafacials, and microneedling. They assess your skin concerns and tailor treatments to suit you. I’ve really noticed a huge difference since following their care plan and always feel very comfortable. The staff are friendly and it’s always easy to park."

    — Hannah-joy Lewisopen

    Google Reviews

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  • "I have been coming to Ascot Medispa for over a year now and have received a number of treatments. Natalie and Liv are very friendly, always smiling and carry out treatments with such professionalism. I highly recommend Ascot Medispa for any treatment you would want do; from laser treatment, hydrofacials, chemical peels, Botox the list is endless!!"

    —Natalia Boaventura-Hawleyopen

    Google Reviews

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  • "I cannot recommend this place enough. From the moment I arrived, I felt so welcomed and completely at ease by Natalie and her team. Everything was explained clearly, with treatments tailored to suit my skin no pressure, just honest, professional advice which was really reassuring. The whole experience was relaxed, with plenty of laughs along the way. I have already noticed a difference and genuinely look forward to going back. Such a warm, professional, and friendly place!"

    —Sukhy

    Google Review

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  • "I want to sincerely thank Natalie and her incredible team at Ascot Medi Spa. While I’ve always had good skin, since turning 40, I noticed I was losing my glow, and like many of us, I developed more wrinkles. I’m not a fan of fillers or Botox, so I was looking for a different solution. Natalie recommended a micro-needling treatment combined with polynucleotides, and I’m so glad I trusted her advice. The treatment completely transformed my skin and gave me that radiant glow I was hoping for. The results exceeded my expectations! I highly recommend this treatment to anyone looking to rejuvenate their skin naturally. I’ll definitely be doing it regularly from now on."

    —Claire Andrisaniopen

    Google Review

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READY?

Regenerate naturally. Restore from within.

Book your free consultation to discuss whether polynucleotide treatments are right for your skin.

Make an Enquiry

Have a question or would like to learn more about our treatments?

Send us a message - our friendly team will be delighted to assist and help you take the next step towards radiant, confident skin.